Sample Exam Questions

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Domain III Pharmaceuticals and Radiopharmaceuticals
B. Prepare radiopharmaceutical kits, perform quality control and evaluate results.
1. What is being evaluated with chromatography testing of technetium radiopharmaceuticals?

1. Aluminum Contamination
2. Molybdenum breakthrough
3. Radionuclidic purity
4. Radiochemical purity
5. Chemical purity

Domain V Clinical Procedures
I. Prepare equipment and perform examinations.
2. The use of elliptical and/or body contour orbits in SPECT imaging should result in improved:

1. Temporal resolution
2. Spatial resolution
3. Reconstruction times
4. Acquisition times
5. Patient comfort

Domain V Clinical Procedures
B. Imaging equipment components and operation.
3. Which of the following variables does not affect spatial resolution in nuclear medicine imaging systems?

1. Physical design of the collimator
2. Material of which the collimator is constructed
3. Energy of the gamma rays being counted
4. Computer matrix pixel size
5. Byte vs. word acquisition mode

Domain IV Instrumentation Operation and QC
A. Non-imaging equipment components and operation.
4. Full width at half maximum (FWHM) is often used as a measure of:

1. Uniformity
2. Sensitivity
3. Intensity
4. Resolution
5. Dead time

Domain V Clinical Procedures
J. Evaluate imaging quality.
5. Uncorrected flood field nonuniformities cause ____________ artifacts in tomographic reconstruction.

1. Irregular
2. Dropout
3. Circular
4. Undulating
5. Linear

Domain IV Instrumentation Operation and QC
B. Imaging equipment components and operation.
6. How many 16-bit words of memory are required for a 64 x 64 byte mode image?

1. 2,048
2. 4,096
3. 16,384
4. 32,768
5. 65,535

Domain V Clinical Procedures
J. Evaluate imaging quality.
7. What are areas of prolonged retention of Xe-133 in the lungs associated with?

1. Reduced trapping in the lung
2. Obstructive lung disease
3. Pulmonary emboli
4. Bacterial pneumonia
5. Septal penetration

Domain V Clinical Procedures
I. Prepare equipment and perform examinations.
8. A patient is to undergo a multiple-gated cardiac blood-pool study with the heart cycle divided in 20 frames. The patient is in normal sinus rhythm and has a heart rate of 68 bpm. The computer should lock in at what time per frame for this study?

1. 44 milliseconds
2. 56 milliseconds
3. 0.29 seconds
4. 1.5 seconds
5. 3.4 seconds

Domain V Clinical Procedures
J. Evaluate imaging quality.
9. Which of the following myocardial perfusion patterns suggest that the patient has myocardial ischemia?

1. Abnormal resting Tc-MIBI, Abnormal Stress Tc-MIBI
2. Abnormal resting Tc-MIBI, Normal Stress Tl-201
3. Normal resting Tc-MIBI, Normal Stress Tl-201
4. Abnormal resting Tl-201, Abnormal Stress Tc-MIBI
5. Normal resting Tl-201, Abnormal Stress Tl-201

Domain V Clinical Procedures
N. Prepare and perform cardiac monitoring and/or assist with stress testing.
10. Ventricular depolarization occurs just before the ventricles contract, expelling blood forward into the pulmonary artery and aorta. What represents this action on the EKG strip?

1. QA complex
2. ST complex
3. QRS complex
4. RS complex
5. PQR complex

Domain II Radiation Safety and Regulations
F. Department of Transportation (DOT) – radiopharmaceutical transport.
11. At what distance is the exposure rate (in mR/hr) indicated by a package's transport index measured?

1. At the surface
2. At 1 meter from the surface
3. At 3 meters from the surface
4. At 6 meters from the surface
5. Transport index doesn’t have anything to do with exposure, all packages, radioactive or not, have a T.I.

Domain II Radiation Safety and Regulations
C. Monitoring protocols and requirements.
12. According to NRC, an unrestricted area is one in which a person would receive a radiation dose of less than:

1. 2 mrem/hr
2. 5 mrem/hr
3. 10 mrem/hr
4. 20 mrem/hr
5. 50 mrem/hr

Domain II Radiation Safety and Regulations
B. Protection techniques and calculations.
13. The dose rate during preparation of a radiopharmaceutical is 1.66 mrem/hr. With this rate reduced by 2 HVLs, how many hours would it take a worker to accumulate 10 mrems?

1. 3
2. 6
3. 12
4. 24
5. 48

Domain V Clinical Procedures
A. Knowledge and performance of nuclear medicine procedure.
14. In a euthyroid patient, which of the following describes the result of Cytomel (T3) administration for 8 days prior to a radioactive iodine thyroid uptake?

1. Elevated protein bound iodine
2. Suppressed "cold" nodules
3. Increased thyroid uptake
4. Decreased thyroid uptake
5. No variation in uptake

Domain V Clinical Procedures
P. Calculate the results of a non-imaging study.
15. A well counter is set to collect 10,000 counts or to stop after 5 minutes. The counter stops at 2 minutes. What is the count rate (in cpm)?

1. 2,000
2. 5,000
3. 10,000
4. 20,000
5. 200,000

Domain I Radiation Physics and Detection
B. Measurement of radioactivity and decay calculations.
16. If a vial containing Tl-201 is found to have an activity of 10.0 mCi at 8 a.m. on Monday, how much activity would remain at 10 a.m. on Friday provided no dose was drawn from this vial (in mCi)?

1. 86.5
2. 4.03
3. 3.94
4. 3.10
5. 2.55

Domain II Radiation Safety and Regulations
E. Nuclear Regulatory Commission (NRC).
17. High Radiation Area signs are to be posted in areas where exposures greater than ____________ mrem/hr are measured at 30 cm from the source or from any surface through which the radiation penetrates:

1. 5
2. 10
3. 50
4. 100
5. 500

Domain IV Instrumentation Operation and QC
I. Imaging equipment, components and operation.
18. When a zoom is used during a 64 x 64 byte mode computer acquisition:

1. The computer automatically switches to a larger matrix size
2. The field of view is increased
3. A spatial filter must be used to smooth away the adverse affects of this technique
4. Spatial resolution is increased
5. More computer memory is needed

Domain IV Instrumentation Operation and QC
A. Non-imaging equipment, components and operation.
19. Which of the following quality control tests should be performed on a dose calibrator after a power outage?

1. Nothing needs to be checked if QC was performed in the last 24 hours
2. Constancy
3. Linearity
4. Geometry
5. Sensitivity

Domain V Clinical Procedures
M. Process and evaluate computer generated data.
20. When processing a gated blood pool study, incorrectly placing the background region over part of the aorta will have what effect on the resulting EF calculation?

1. The result will be higher than patient’s true EF
2. The result will be lower than patient’s true EF
3. It will have no effect; the background in the region of the aorta is insignificant
4. It will have no effect: the background data is only used to smooth the resulting volume curve
5. It depends; the effect is different depending on whether the patient’s heart function is abnormal or normal to begin with

Domain III Pharmaceuticals and Radiopharmaceuticals
F. Label blood components with radiopharmaceutical according to protocol.
21. When labeling leukocytes with In-111 oxine, what is the next step in the procedure after blood has been drawn in a syringe containing an anticoagulant?

1. Centrifuge the sample at 200 g. for 5 minutes
2. Centrifuge the sample at 2000 g. for 5 minutes
3. Sediment the sample for 50 to 60 minutes
4. Add the In-111 oxine
5. Add ascorbic acid

Domain III Pharmaceuticals and Radiopharmaceuticals
A. Elute radionuclide generator, perform and evaluate quality control tests.
22. The limit for Mo-99 contamination in a solution of Tc-99m is no more than;

1. 1 uCi Mo-99 per mCi Tc-99m
2. 0.15 uCi Mo-99 per mCi Tc-99m
3. 5 uCi Mo-99 per mCi Tc-99m
4. 0.15 uCi Mo-99 per ml Tc-99m solution
5. 5 uCi Mo-99 per ml Tc-99m solution

Domain V Clinical Procedures
J. Evaluate image quality.
23. What is the most likely cause of activity seen in the liver and spleen during a perfusion lung scan?

1. Normal physiology and biodistribution
2. Left-to-right cardiac shunt
3. Dissociation and oxidation to free pertechnetate
4. COPD
5. MAA particles smaller than 5 microns

Domain IV Instrumentation Operation and QC
A. Non-imaging equipment, components and operation.
24. According to national standards, how often should the activity linearity of a dose calibrator be measured?

1. Each day of use
2. Weekly
3. Monthly
4. Quarterly
5. Annually

Domain V Clinical Procedures
N. Prepare and perform cardiac monitoring and/or assist with stress testing.
25. Which of the following situations would be considered an absolute contraindication for performing adenosine pharmacological stress testing?

1. Patient drank a couple cups of caffeinated coffee 2 hours prior
2. Patient ate a solid meal 2 hours prior
3. Patient had a colonoscopy 1 week prior
4. Patient had a known myocardial infarction 6 months previously
5. SPECT imaging is not available at this site

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